Introimage

Programme

Click here to download the Detailed Programme.

List of invited speakers

Keynotes lectures
Orlando D. SchärerDepartment of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, USA
Studying nucleotide excision repair and interstrand crosslink repair with the help of chemical approaches
Lei LiDepartment of Experimental Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
DNA interstrand crosslink repair and Fanconi anemia
Wim VermeulenDepartment of Genetics, Erasmus MC, Rotterdam, The Netherlands
Mammalian nucleotide excision repair
 
Nucleotide excision repair - USA
Ben Van HoutenDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, PA, USA
Structure-function studies of bacterial nucleotide excision repair proteins: Watching DNA repair, one molecule at a time
Nicholas E. GeacintovChemistry Department, New York University, New York, NY, USA
The impact of base sequence context on the removal of DNA lesions by NER
Vesna Rapic-OtrinDepartment of Microbiology and Molecular Genetics, School of Medicine, Cancer Institute, University of Pittsburgh, PA, USA
DDB1-CUL4B(DDB2) E3 ligase-dependent ubiquitination of the core histones destabilizes mononucleosomes containing UV damaged DNA
 
Inter - strand crosslink repair / Fanconi anemia - USA
Puck KnipscheerHarvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, Boston, MA, USA
The molecular mechanism of replication-coupled DNA interstrand crosslink repair
Karen M. VasquezDepartment of Carcinogenesis, Science Park-Research Division, The University of Texas M.D. Anderson Cancer Center, Smithville, TX, USA
Targeting and processing of site-specific DNA interstrand crosslinks
Laura J. NiedernhoferDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, PA, USA
Senescence and aging as a consequence of unrepaired crosslinks
 
Nucleotide excision repair - EU
Jean-Marc EglyDepartment of Functional Genomics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch Graffenstaden, France
NER factors are recruited to the promoters of activated genes and help chromatin modifications
Hanspeter NaegeliInstitute of Pharmacology and Toxicology, University of Zürich-Vetsuisse, Zürich, Switzerland
Bipartite recognition of bulky base lesions
Simon H. ReedDepartment of Pathology, School of Medicine, Cardiff University, Cardiff, UK
Yeast global genome repair proteins promote UV induced chromatin remodeling required for efficient nucleotide excision repair
Caroline KiskerRudolf-Virchow Center for Experimental Biomedicine, University of Wuerzburg, Wuerzburg, Germany
XPanDing archaeal XPD structures to get a grip on human DNA repair
Leon H. MullendersDepartment of Toxicogenetics, Leiden University Medical Center, Leiden, The Netherlands
UV induced NER complex assembly and signalling in mammalian cells
 
Inter - strand crosslink repair / Fanconi anemia - EU
Peter McHughWeatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
Mechanistic insights into a human nuclease required for DNA cross-link repair
KJ PatelMedical Research Council, Laboratory for Molecular Biology, Cambridge, UK
Title pending

List of invited local speakers

Nucleotide excision repair
Barbara TudekInstitute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal
Erich HeidenreichDepartment of Medicine, Medical University of Vienna, Vienna, Austria
Evidence for antimutagenic as well as mutagenic properties of nucleotide excision repair in non-replicating yeast cells
Miroslav PiršelLaboratory of Molecular Genetics, Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Slovakia
DNA repair, apoptosis and cell cycle control in ERCC3/XPB mutant cell lines
 
Inter - strand crosslink repair / Fanconi anemia
Margaret ZdzienickaCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland
Genetic basis of the cellular sensitivity to cross-linking agents and PARP inhibitors – implications for cancer treatment
Wojciech NiedzwiedzInstitute of Genetics and Biotechnology, Faculty of Biology, Warsaw University, Poland; Department of Medical Oncology, Oxford University, Oxford, UK
FANCM: molecular matchmaker at the replication fork
Viktor BrabecInstitute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic
DNA interstrand crosslinking by new antitumor dinuclear PtII complexes
Miroslav ChovanecLaboratory of Molecular Genetics, Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Slovakia
Pso2-dependent and -independent arms of the ICL repair in Saccharomyces cerevisiae
Marcin SzaumkesselDepartment of Environmental Mutagenesis, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
DNA methylation profiling of Fanconi/BRCA pathway genes in laryngeal squamous cell carcinoma